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https://evnuir.vnu.edu.ua/handle/123456789/22813| Title: | Morphogenesis of the zero-stage osteonecrosis formation оf the lower jaw based on the use of aminobisphosphonates |
| Authors: | Pikalyuk, Vasyl S. Mostovoy, Semen O. Peshkov, Mykhailo V. Tkach, Gennady F. Shevchuk, Tatiana Ya. Aponchuk, Lyudmila S. Usova, Oksana V. |
| Affiliation: | Волинський національний університет імені Лесі Українки, професор кафедри анатомії людини медичного факультету, доктор медичних наук, професор Лікар-стоматолог, кандидат медичних наук Доктор фізико-технічних наук, професор Київський національний університет імені Т. Г. Шевченка, професор кафедри анатомії, доктор медичних наук, професор Волинський національний університет імені Лесі Українки, професор, завідувач кафедри анатомії людини медичного факультету, кандидат біологічних наук, доцент Волинський національний університет імені Лесі Українки, старший викладач кафедри анатомії людини медичного факультету, кандидат біологічних наук Волинський національний університет імені Лесі Українки, професор кафедри фізичної терапії та ерготерапії, кандидат біологічних наук, доцент медичного факультету, кандидат біологічних наук, доцент |
| Bibliographic description (Ukraine): | Pikalyuk V. S., Mostovoy S. O., . Peshkov M. V, Tkach G. F., Shevchuk T. Ya., Aponchuk L. S., Usova O. V. (2022). Morphogenesis of the zero-stage osteonecrosis formation оf the lower jaw based on the use of aminobisphosphonates. Світ Медицини та Біології. 4(82), 235-240. DOI : https://doi.org/10.26724/2079-8334-2022-4-82-235-240 |
| Journal/Collection: | Світ медицини та біології |
| Issue: | 4 (82) |
| Issue Date: | Mar-2022 |
| Date of entry: | 18-Sep-2023 |
| Publisher: | Полтавський державний медичний університет |
| Country (code): | UA |
| DOI: | https://doi.org/10.26724/2079-8334-2022-4-82-235-240 |
| UDC: | 616.716.4:615.015 |
| Keywords: | aminobisphosphonate osteonecrosis osteocytic osteolysis lower jaw |
| Page range: | 235-240 |
| Abstract: | The dynamics of morphostructural changes in the mandibular bones of laboratory white rats after a 3-month exposure to pamidronic acid at the dose of 63 mg/kg was studied. Light microscopy methods were used, including qualitative and quantitative characteristics in assessing the structural state of the bone through the parameters that characterize the histoarchitectonics of the lower jaw using indices and their abbreviations proposed by the committee on histomorphometric nomenclature of American Society for Bone and Mineral Research. Three new functional indices for assessing physiological processes in bones were studied. It was established that administration of pamidronic acid to laboratory white rats for 3 months leads to myelofibrosis and focal osteosclerosis with osteodystrophic changes, similar to the processes that develop in ossifying osteitis |
| URI: | https://evnuir.vnu.edu.ua/handle/123456789/22813 |
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| Content type: | Article |
| Appears in Collections: | Наукові роботи (FM) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| SMB-2022-04-235.pdf | 2,08 MB | Adobe PDF | View/Open |
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